Over the past months, the PROPHET Team has been working on several academic papers focusing on personalised prevention. In total, more than 15 publications were published so far. Each one covers an important aspect of personalised prevention or is connected to it such as chronic diseases, genetic tests, non-communicable diseases, pharmacogenomics:
- Gris, A. V., Cristiano, A., Di Berardino, F., Giacobini, E., Tricomi, V., Pezzullo, A. M., … & Cuore, S. Pre-emptive pharmacogenetic testing in Italy: a review of evidence and multidisciplinary consensus on key priorities for implementation. Frontiers in Public Health (2025).
- Maio A., Farina S., Osti T., Di Grande S., Pastorino R., Boccia S. Scanning the horizon of personalized prevention research: an overview of ongoing European funded initiatives. Frontiers in Public Health, 13:1561328 (August 2025). https://doi.org/10.3389/fpubh.2025.1561328
- Villiers C.B.d., Plans-Beriso E., Erady C., et al. Biomarkers for Personalised Primary or Secondary Prevention in Cardiovascular Diseases: A Rapid Scoping Review. International Journal of Molecular Sciences, 26, 9346 (September 2025). https://doi.org/10.3390/ijms26199346
- Scarsi N., Taha A., Farina S., Osti T., Russo L., Maio A., Pastorino R., Boccia S. Mapping the state-of-the-art of the barriers for personalized preventive approaches worldwide: A scoping review of reviews. PLoS ONE, 20(10): e0335444 (2025). https://doi.org/10.1371/journal.pone.0335444
- Kreeftenberg L. L., Henneman L., Louati C., et al. Personalised Prevention: What Patients and Citizen Advocates Want for Better Engagement – A Qualitative Study (2025).
- Pezzullo A. M., Valz Gris A., Scarsi N., et al. A scoping review of the assessment reports of genetic or genomic tests reveals inconsistent consideration of key dimensions of clinical utility. Journal of Clinical Epidemiology (2025). https://doi.org/10.1016/j.jclinepi.2025.111729
- Valz Gris A., Vicente A. M., Boccia S. Implementation of genetic tests for disease prevention: challenges in evidence synthesis across clinical utility domains. European Journal of Public Health, 35(3):399–400 (April 2025). https://doi.org/10.1093/eurpub/ckaf047
- Roelofsen A. H. A., Kreeftenberg L. L., van El C. G., et al. Barriers and facilitators for implementing a pharmacogenetic passport: lessons learned from reusing sequencing data. Pharmacogenomics, 26(5–6):143–156 (May 2025). https://doi.org/10.1080/14622416.2025.2504862
- Farina S., Osti T., Russo L., et al. The current landscape of personalised preventive approaches for non-communicable diseases: A scoping review. PLoS ONE, 20(1): e0317379 (January 2025). https://doi.org/10.1371/journal.pone.0317379
- Kreeftenberg L. L., Henneman L., Ket J. C., Cornel M. C., Van El C. G. Engagement of patients and the public in personalised prevention in Europe using genomic information: a scoping review. Frontiers in Public Health, 12 (September 2024). https://doi.org/10.3389/fpubh.2024.1456853
- Pastorino R., Pezzullo A. M., Osti T., et al. The PROPHET project paves the way for personalized prevention in the future healthcare. European Journal of Cancer Prevention, 33(5):387–389 (September 2024). https://doi.org/10.1097/CEJ.0000000000000873
- Plans-Beriso E., Babb-de-Villiers C., Petrova D., et al. Biomarkers for personalised prevention of chronic diseases: a common protocol for three rapid scoping reviews. Systematic Reviews, 13, 147 (June 2024).
https://doi.org/10.1186/s13643-024-02554-9 - Van Steijvoort E., Goossens K., Demesure K., et al. Sharing behavior and health care utilization following direct-to-consumer genetic testing: a systematic review. Open Research Europe. https://doi.org/10.12688/openreseurope.19751.2
- Costa C., Lopes F., Costa A., et al. Conceptual Model for Health Impact Assessment of Personalized Prevention Policies. European Journal of Public Health. https://doi.org/10.1093/eurpub/ckae144.1571
- Costa A., Cardoso M. L., Carvalho A., et al. Barriers to Personalised Prevention: Perspectives from a Multi-Stakeholder Consultation. European Journal of Public Health. https://doi.org/10.1093/eurpub/ckae144.1321
- Cardoso M. L., Costa A., Rasga C., et al. Unveiling pharmacogenomics: insights from Portuguese pharmacists on quaternary prevention. European Journal of Public Health. https://doi.org/10.1093/eurpub/ckae144.1861
- Vicente A. M. The 1+Million Genomes Maturity Level Model for Genomics in Healthcare. European Journal of Public Health. https://doi.org/10.1093/eurpub/ckae144.778
- Phillips A., Van Steijvoort E., Siermann M., et al. Genomic findings with familial implications: agenda setting in light of mainstreaming. Open Research Europe. https://doi.org/10.12688/openreseurope.19128.1